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EPHB2 — RELN

Text-mined interactions from Literome

Simó et al., Cereb Cortex 2007 (MAP Kinase Signaling System) : Although rat sarcoma viral oncogene was weakly activated upon Reelin treatment, pharmacological inhibition of the PI3K pathway blocked Reelin dependent ERK activation , which indicates cross talk between the ERK and PI3K pathways ... Our findings demonstrate that Reelin triggers ERK signaling in an SFK/mDab1- and PI3K dependent manner and that ERK activation is required for Reelin dependent transcriptional activation and the detachment of neurons migrating from the SVZ
Bouché et al., Cell Res 2013 : Reelin induces EphB activation ... Here, we demonstrate that Reelin binds to the extracellular domains of EphB transmembrane proteins, inducing receptor clustering and activation of EphB forward signaling in neurons, independently of the ` classical ' Reelin receptors, ApoER2 and VLDLR