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AKT1 — ETV6

Text-mined interactions from Literome

Nguyen et al., J Biol Chem 2001 (Translocation, Genetic) : However, LY294002 did not alter STAT5 tyrosine phosphorylation, indicating that STAT5 and protein kinase B activation mediated by TEL-JAK2 are independent signaling pathways
Tognon et al., Cancer Res 2001 (Cell Transformation, Neoplastic...) : The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation ... We now report that ETV6-NTRK3 expression in NIH3T3 cells leads to constitutive activation of Mek1 and Akt , as well as to constitutively high expression of cyclin D1
Wheadon et al., Blood 2003 : We demonstrate that TEL/PDGFbetaR expression augmented IL-3 induced activation of PKB , STAT5, ERK1/2, p38, and JNK1/2
Jin et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : Here, we define some aspects of the molecular mechanisms regulating ETV6-NTRK dependent Ras-Erk1/2 and PI3K-Akt activation