Gene interactions and pathways from curated databases and text-mining

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AKT1 — FGFR2

Text-mined interactions from Literome

Jang et al., Blood Cells Mol Dis 2002 (Leukemia...) : Furthermore, overexpression of FGFR2AT-I resulted in increased AKT and MAPK activation, conferring a survival advantage
Pan et al., Mol Biol Cell 2004 : When viewed collectively, it appears that the association between the KGFR and RSK plays an important role in KGF induced Akt activation and consequently in the protective effects of KGF on epithelial cells
Huang et al., Mol Carcinog 2009 (Liver Neoplasms, Experimental) : Analysis of activation of Erk, JNK, and PI3K related AKT signaling pathways indicated that in contrast to FGFR1, FGFR4 failed to sustain Erk activation and did not activate AKT
Mavila et al., PloS one 2012 (Liver Neoplasms) : FGF Receptor ( R ) activation resulted in the downstream activation of MAPK, PI3K-AKT , and ß-catenin pathways, as well as cellular proliferation