◀ Back to BCL2

BCL2 — FASLG

Text-mined interactions from Literome

Srivastava et al., J Exp Med 1999 : Bcl-2 mediated drug resistance : inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes ( NFAT ) -induced Fas ligand transcription ... We have found that Bcl-2 overexpression leads to the prevention of chemotherapy ( paclitaxel ) -induced expression of FasL and blocks paclitaxel induced apoptosis
Verbeke et al., Clin Exp Immunol 2000 (Infectious Mononucleosis) : In accordance with a high rate of apoptosis ( up to 2.37 % ) within the expanded T cell population, Bcl-2 expression was drastically reduced and FasL expression remarkably increased
Simizu et al., Jpn J Cancer Res 2000 : Bcl-2 inhibits calcineurin mediated Fas ligand expression in antitumor drug treated baby hamster kidney cells ... Overexpression of Bcl-2 and cyclosporin A treatment inhibited the nuclear import and FasL expression, and as a result, both inhibited apoptosis
Biswas et al., Mol Cell Biochem 2001 (Breast Neoplasms...) : Overexpression of Bcl-XL leads to inhibition of paclitaxel induced FasL expression and apoptosis
Tung et al., Am J Physiol Heart Circ Physiol 2003 : These changes in the Fas-Fas ligand pathway and Bcl-2 mitochondrial apoptosis regulation are enhanced by complete suppression of antiapoptotic FADD-like IL-1beta converting enzyme inhibitory protein ( FLIP ) ( from 30.5 to 0.0 %, P < 0.01 ) and Bcl-xL ( from 22.5 to 0.1 %, P = 0.03 ) expression among these cells from the earliest days after gene transfer
Hasan et al., BMC microbiology 2006 : Expression of Fas ligand and apoptotic proteins is found in leprosy lesions and M. leprae has been shown to activate pro-apoptotic Bcl-2 genes, Bak and Bax
Park et al., Toxicol In Vitro 2008 (Leukemia) : However, the elevated levels of FasL expression induced by streptochlorin were not reduced by Bcl-2 overexpression
Gravina et al., Prostate 2010 (Neoplasms, Experimental...) : This combined treatment up-regulated the expression of FasL , phospho-FADD, p16 ( INKA ), Bax, Bak, and p21 ( WAF1 ), and inhibited FLIP, Bcl-2, and Bcl-XL expression ... This combined treatment up-regulated the expression of FasL , phospho-FADD, p16 ( INKA ), Bax, Bak, and p21 ( WAF1 ), and inhibited FLIP, Bcl-2 , and Bcl-XL expression
Oh et al., J Biol Chem 2011 : Moreover, we found that STAT3 enhanced survival of activated T-cells by up-regulating OX-40 and Bcl-2 while down regulating FasL and Bad expression, suggesting that similar to role of FoxOs in regulating the lifespan of worms, STAT3 and FoxO pathways converge to regulate lifespan of T-lymphocytes
Fulda et al., Cancer Res 1998 (Neuroblastoma) : After Doxo treatment, enhanced CD95/CD95-L expression and caspase-8 activation were not blocked by Bcl-2 or Bcl-X ( L ) and were found in cells with a mitochondrial transmembrane potential ( delta psi ( m ) ) that was still normal ( delta psi ( m ) high cells )