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IL8 — PRKACB

Text-mined interactions from Literome

Zhang et al., J Immunol 1992 : In contrast, induction of IL-8 by RA was inhibited by both 1- ( 5-isoquinoline sulfonamide and N- ( 2-gamidinoethyl ) -5-isoquinoline sulfonamide, suggesting the participation of PKA in the induction of IL-8 by RA ... However, activation of PKA by addition of cAMP analogues was not sufficient to induce IL-8 expression
Grandjean-Laquerriere et al., Cytokine 2005 : In this study, we use specific inhibitors to investigate the role of both PKA- and PKC mediated pathways in the regulation of UVB induced IL-8 expression in NCTC 2544 cell line ... Finally, we concluded that a cAMP independent PKA activation and a PKC associated pathway are probably involved in the regulation of UVB induced IL-8 synthesis in human keratinocytes
Hirano et al., Eur J Pharmacol 2007 : The synergistic production of MCP-1 and IL-8 by PGD2 was mimicked by dibutyryl cAMP ( db-cAMP ) and was inhibited by a protein kinase A (PKA) inhibitor
Simeone et al., Int J Oncol 2007 (Breast Neoplasms...) : Protein kinase A (PKA) and protein kinase C ( PKC ) are activated by COX-2 and are involved in IL-8 regulation ... Activation of PKC, not PKA , increased IL-8 production and invasion in MCF-7 cells
Gross et al., Gastroenterology 1995 : The aim of this study was to improve the understanding of the regulation of IL-8 synthesis by investigating the roles of protein kinase C ( PKC ), protein kinase A (PKA) , and protein tyrosine kinase ( PTK ) in the induction of IL-8
Beales et al., Cytokine 1997 : The aim of this study was to investigate the roles of protein kinase A (PKA) , protein kinase C ( PKC ), protein tyrosine kinase ( PTK ) and intracellular calcium in the induction of IL-8 production by gastric epithelial cells ... Stimulation of PKA with forskolin or dibutyryl cyclic adenosine monophosphate or inhibition with H89 had no effect on IL-8 production
Ding et al., Biochem Biophys Res Commun 1997 : It is concluded that HP and its toxin can increase IL-8 expression in endothelial cells, and the expression of IL-8 elicited by HP toxin, TNF-alpha, and LPS is partially dependent on PTK but not PKA or PKC activation
Jaspers et al., J Cell Physiol 1998 (Adenocarcinoma, Bronchiolo-Alveolar...) : Exposure to ozone increased interleukin 8 expression and transcription factor activities in a protein tyrosine kinase ( PTK ) -dependent and protein kinase A (PKA) dependent , yet protein kinase C ( PKC ) -independent, manner