Gene interactions and pathways from curated databases and text-mining

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AIF1 — IL6

Text-mined interactions from Literome

Kimura et al., J Immunol 2007 (Arthritis, Rheumatoid...) : AIF-1 induced the proliferation of cultured synovial cells in a dose dependent manner and increased the IL-6 production of synovial fibroblasts and PBMC
Yamamoto et al., Immunol Lett 2011 (Disease Models, Animal...) : These findings suggest that AIF-1 , which can induce the migration of fibroblasts and the production of IL-6 in affected skin tissues, is an important molecule promoting fibrosis in GVHD ... Although the biological function of AIF-1 has not been completely elucidated, AIF-1 can induce IL-6 secretion on mononuclear cells and fibroblast chemotaxis