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AIF1 — IL6
Text-mined interactions from Literome
Kimura et al., J Immunol 2007
(Arthritis, Rheumatoid...) :
AIF-1 induced the proliferation of cultured synovial cells in a dose dependent manner and
increased the
IL-6 production of synovial fibroblasts and PBMC
Yamamoto et al., Immunol Lett 2011
(Disease Models, Animal...) :
These findings suggest that
AIF-1 , which can
induce the migration of fibroblasts and the production of
IL-6 in affected skin tissues, is an important molecule promoting fibrosis in GVHD ... Although the biological function of AIF-1 has not been completely elucidated,
AIF-1 can
induce IL-6 secretion on mononuclear cells and fibroblast chemotaxis