Aghdasi et al., Proc Natl Acad Sci U S A 2001
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By contrast, activated phosphorylated p38 is markedly augmented in FKBP12 ( -/- ) cells and the p21 up-regulation is prevented by an inhibitor of p38 Guan et al., J Invest Dermatol 2009
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However, neither Nckalpha nor Nckbeta was required for the activation of the PDGF receptor, p21 activated protein kinase ( Pak1 ), AKT, extracellular signal regulated kinase ( ERK ) 1/2, or p38MAP by PDGF-BB