◀ Back to IL6

APP — IL6

Text-mined interactions from Literome

Derfalvi et al., Cell Biol Int 2000 (Acute-Phase Reaction) : However, both IL-6 stimulated junB gene expression ( junB mRNA ) and biosynthesis of type II APP ( alpha2-macroglobulin, fibrinogen, haptoglobin ) were strongly inhibited by the GH
Verbeek et al., J Histochem Cytochem 2002 : Both the cytokine interferon-gamma and the lysosomotropic drug chloroquine, but not the cytokines interleukin (IL)-1, IL-6 , or tumor necrosis factor-alpha (TNF-alpha), induced an accumulation of APP in newly formed multivesicular body-like organelles
Milosavljević et al., Gen Physiol Biophys 2003 (Acute-Phase Reaction) : CCAAT/enhancer binding proteins (C/EBP) alpha, -beta and -delta play an important role in mediating I interleukin-6 (IL-6) dependent expression of acute-phase protein (APP) genes in liver during acute-phase ( AP ) response
Shaftel et al., Journal of neuroinflammation 2008 (Alzheimer Disease...) : The role of interleukin-1 in neuroinflammation and Alzheimer disease : an evolving perspective
Kolkhof et al., Biochem Biophys Res Commun 2010 : We show here that endogenous and plant derived inhibitors of the Na ( + ) /K ( + ) -ATPase, i.e. the cardiac glycosides ouabain and digitoxin, inhibit IL-1beta- and IL-6 induced APP expression in human hepatoma cells and primary human hepatocytes ( PHH ) at nanomolar concentrations
Antonioli et al., J Pharmacol Exp Ther 2010 (Body Weight...) : APP , EHNA, and dexamethasone counteracted the increments of spleen weight, ameliorated macroscopic and microscopic indexes of inflammation, and reduced TNF-a, IL-6 , and MDA levels
Campos et al., J Immunol 1993 : In growing cultures, the IL-6 and IL-11 stimulation of thiostatin and hemopexin is enhanced by TGF-beta, whereas the stimulation of other APP is reduced
Reiter et al., J Leukoc Biol 1994 : Neither ABPP nor tilorone induced TNF or IL-6
Gabay et al., Clin Exp Immunol 1995 (Carcinoma, Hepatocellular) : Since previous studies on the contributions of cytokine inhibitors in connective tissues diseases suggested that IL-1 and tumour necrosis factor-alpha (TNF-alpha) might play an important role in the regulation of CRP, we decided to examine in more detail the respective roles of IL-1 beta, IL-6 , and TNF-alpha and their inhibitors in the production of APP by human primary hepatocytes versus the hepatoma cell line PLC/PRF/5
Schaper et al., FEBS Lett 1997 (Carcinoma, Hepatocellular) : It was shown that IL-6 and IL-6-type cytokines activate the so-called JAK/STAT pathway and finally regulate APP expression in liver cells
Vadas et al., Clin Exp Immunol 1997 : Although dexamethasone potentiated IL-6 induced APP expression in HepG2 cells, it suppressed sPLA2 expression in a dose dependent manner