Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK7 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ NOS1 ▸ CCL2 ▸
CD14 ▸ ICAM1 ▸ JUN ▸ IL4 ▸ CPOX ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPF ▸ HNRNPH1 ▸
PTBP2 ▸ IL15 ▸ IL3 ▸ IL33 ▸ IL32 ▸ IL19 ▸ IL37 ▸
IL21 ▸ IL20 ▸ IL9 ▸ IL24 ▸ IL22 ▸ IL11 ▸ IL7 ▸
IL16 ▸ IL31 ▸ IL25 ▸ IL34 ▸ IL27 ▸ IL26 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP3 ▸ CASP1 ▸ CXCL10 ▸ CASP6 ▸ CASP9 ▸ CASP4 ▸ CASP8 ▸
CASP2 ▸ CASP10 ▸ CASP14 ▸ CASP5 ▸ CASP16 ▸ CASP7 ▸ CASP12 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ GRAP2 ▸ RNF19A ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ CCL3 ▸ TLR1 ▸
VEGFA ▸ TLR7 ▸ CFP ▸ ANXA6 ▸ TLR5 ▸ CRK ▸ LANCL1 ▸
TLR6 ▸ TLR8 ▸ CD86 ▸ STAT1 ▸ GPI ▸ TLR10 ▸ MMP2 ▸
CD79A ▸ CD40 ▸ HMGB1 ▸ MMP1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ POLDIP2 ▸ CD80 ▸ IRF3 ▸ STAT3 ▸ MYD88 ▸
MIP ▸ NOX4 ▸ MMP3 ▸ MMP13 ▸ TP63 ▸ NOX5 ▸ NOX3 ▸
MUC2 ▸ MUC1 ▸ MMP8 ▸ CA2 ▸ MMP14 ▸ TGFB1 ▸ IRAK1 ▸
CXCL1 ▸ MUC7 ▸ MMP12 ▸ MMP11 ▸ MMP26 ▸ MMP28 ▸ MMP24 ▸
MMP16 ▸ CD46 ▸ MUC16 ▸ CXCL2 ▸ MMP27 ▸ MMP21 ▸ MMP15 ▸
MMP7 ▸ MUC4 ▸ MMP17 ▸ RABEPK ▸ MMP19 ▸ MMP10 ▸ MMP25 ▸
MMP20 ▸ MUC12 ▸ TCF25 ▸ MUC8 ▸ MUC6 ▸ MUC17 ▸ TCF20 ▸
MUC13 ▸ TCF3 ▸ TCF15 ▸ TCF12 ▸ MUC22 ▸ CXCL9 ▸ MUC21 ▸
TCF7 ▸ TCF21 ▸ TCF24 ▸ IKBKG ▸ TCF23 ▸ MUC15 ▸ MUC19 ▸
TCF4 ▸ TCF19 ▸ MUC20 ▸ LYZ ▸ CXCL11 ▸ SERPINE1 ▸ CTR9 ▸
HLA-DRA ▸ WDR61 ▸ CDC73 ▸ LEO1 ▸ CXCL12 ▸ PAF1 ▸ PTGS1 ▸
CXCL13 ▸ CXCL5 ▸ PLA2G4A ▸ LEP ▸ HLA-DRB1 ▸ IRF1 ▸ C1orf228 ▸
MIPEP ▸ ITGB2 ▸ SOD1 ▸ SOD2 ▸ CXCL16 ▸ SOD3 ▸ IRAK4 ▸
CSF3 ▸ CXCL6 ▸ IL23A ▸ CXCL3 ▸ PI3 ▸ IDO1 ▸ CXCL17 ▸
CXCL14 ▸ PGF ▸ PIK3CA ▸ CRH ▸ HDC ▸ PIK3R1 ▸ REL ▸
PDCD11 ▸ HGF ▸ LTB ▸ IRAK3 ▸ SOCS3 ▸ PLA2G1B ▸ MYLIP ▸
EGR1 ▸ CSF1 ▸ SAA1 ▸ SLC25A10 ▸ CD83 ▸ NANOS2 ▸ ICAM5 ▸
NM ▸ ICAM4 ▸ ICAM3 ▸ ICAM2 ▸ IRAK2 ▸ MUC5AC ▸ INS ▸
NUP43 ▸ ARG1 ▸ FAS ▸ BPI ▸ TNPO1 ▸ SETD2 ▸ TBCE ▸
TNFSF11 ▸ EDN1 ▸ SOAT1 ▸ SLPI ▸ IGF1 ▸ CD4 ▸ CEBPB ▸
PTGES ▸ CCR2 ▸ MIF ▸ CREB1 ▸ DUSP1 ▸ CREB5 ▸ DEFB4B ▸
NCF1 ▸ FASLG ▸ CREB3 ▸ CEBPA ▸ HDAC1 ▸ IRF7 ▸ CAT ▸
CCL4 ▸ MDM4 ▸ CCL20 ▸ ARF4 ▸ S100A12 ▸ ARF1 ▸ MDM1 ▸
ARF5 ▸ CRP ▸ ARF3 ▸ IRF2 ▸ SELP ▸ ARF6 ▸ PTX3 ▸
CD69 ▸ MDM2 ▸ MAP3K8 ▸ SRC ▸ IFI44 ▸ HDAC2 ▸ PLD1 ▸
PLG ▸ NGF ▸ RAC1 ▸ GP2 ▸ APOE ▸ GP5 ▸ PLD5 ▸
NFKBIB ▸ GP9 ▸ ARG2 ▸ GP6 ▸ PLD2 ▸ IRF8 ▸ SLC17A5 ▸
IRF4 ▸ PPARG ▸ TNFRSF11B ▸ PLD3 ▸ RBBP4 ▸ PLD6 ▸ CISH ▸
CCR7 ▸ ABCC1 ▸ MTOR ▸ PLD4 ▸ RHOA ▸ HIF1A ▸ CCR5 ▸
APOB ▸ CD40LG ▸ PGD ▸ AGTR2 ▸ CDCA5 ▸ BAX ▸ AVP ▸
PRKCA ▸ ALB ▸ TRAF6 ▸ SERPINB2 ▸ NOD2 ▸ CCL5 ▸ JAK2 ▸
GIT2 ▸ HBD ▸ ZFP36 ▸ SP1 ▸ BDNF ▸ ADAM11 ▸ IL17D ▸
CORT ▸ AHR ▸ MAPKAPK2 ▸ CCND1 ▸ BCL2 ▸ PPARA ▸ TIMP1 ▸
TREM1 ▸ GJA1 ▸ APC ▸ FCER2 ▸ F3 ▸ EGFR ▸ ATF2 ▸
CAV1 ▸ TBK1 ▸ LPL ▸ PDE4B ▸ IL2RA ▸ ODC1 ▸ LIF ▸
LTF ▸ LYN ▸ LCN2 ▸ HSPG2 ▸ SELL ▸ RBBP7 ▸ IL1R1 ▸
IFNA4 ▸ CALM3 ▸ CXCR4 ▸ GNRH1 ▸ IRF5 ▸ STS ▸ LY96 ▸
PLAU ▸ LITAF ▸ IRF9 ▸ BCL10 ▸ ATP5O ▸ ARID4B ▸ TNFSF13B ▸
HSPD1 ▸ CCR3 ▸ PRL ▸ GAL ▸ SLC27A5 ▸ AGTR1 ▸ TNFSF10 ▸
BCL3 ▸ P2RX7 ▸ SAP30 ▸ NCF2 ▸ CYP3A ▸ BTK ▸ UCN ▸
PTK6 ▸ CSRP1 ▸ SPP1 ▸ CD2 ▸ GDNF ▸ PTK7 ▸ ADM ▸
SAP130 ▸ NA ▸ RAF1 ▸ PTK2 ▸ MNAT1 ▸ IFNA2 ▸ IL17A ▸
MLYCD ▸ PARP1 ▸ CCR6 ▸ SUDS3 ▸ TFPI ▸ SIN3A ▸ ATP8A2 ▸
SOCS1 ▸ MT3 ▸ MOCOS ▸ EIF2AK2 ▸ PRDX2 ▸ CCR9 ▸ STAT5A ▸
IL2RB ▸ IFNA13 ▸ CCR10 ▸ CRAT ▸ IFNA14 ▸ ECM1 ▸ ACP2 ▸
IFNA16 ▸ MAP3K14 ▸ FGB ▸ JAK1 ▸ LDLR ▸ MOK ▸ PRG4 ▸
IFNA17 ▸ ECM2 ▸ CCR1 ▸ CD276 ▸ CD8A ▸ PRG2 ▸ TGFB2 ▸
PHKA2 ▸ CEL ▸ RETN ▸ APP ▸ PRG3 ▸ ADAM17 ▸ CD44 ▸
NLRP3 ▸ SPHK1 ▸ IFNA5 ▸ CXCR1 ▸ RELB ▸ CEBPD ▸ SETBP1 ▸
IFNA7 ▸ IFNA1 ▸ MSH3 ▸ CSE ▸ TP53 ▸ IKBKAP ▸ IFNA21 ▸
CCR8 ▸ IFNA8 ▸ SLC22A3 ▸ NEDD9 ▸ IFNA10 ▸ ACE ▸ CCR4 ▸
LIPA ▸ IFNA6 ▸ NOTCH1 ▸ MAP2K1 ▸ ETS2 ▸ GCHFR ▸ CNR2 ▸
NEU1 ▸ WAS ▸ SYK ▸ ANXA1 ▸ SIGLEC7 ▸ MSH5 ▸ IGFBP3 ▸
EDN2 ▸ CRYGEP ▸ MSH4 ▸ ALG1 ▸ F2R ▸ TXN ▸ NOTCH2 ▸
EIF4EBP1 ▸ ATF3 ▸ NOTCH3 ▸ S100A8 ▸ TYK2 ▸ PTPN11 ▸ BCL5 ▸
SERPING1 ▸ OCLN ▸ TF ▸ NOD1 ▸ RAC2 ▸ ABCA1 ▸ MSH2 ▸
CAV3 ▸ TRAM1 ▸ MSH6 ▸ UCP2 ▸ FBXO32 ▸ TRAM2 ▸ TNFRSF1B ▸
CAMP ▸ PLAUR ▸ HDAC11 ▸ SAA2 ▸ CADM1 ▸ BCL9 ▸ SLCO6A1 ▸
NOTCH4 ▸ TNP2 ▸ LTA ▸ MAF ▸ CD55 ▸ HDAC3 ▸ CCL24 ▸
TGFB3 ▸ ABCB1 ▸ PCBD1 ▸ PAM ▸ OLR1 ▸ PLIN2 ▸ TNP1 ▸
APCS ▸ F2RL1 ▸ SAA4 ▸ EDN3 ▸ BCL6 ▸ TNFRSF1A ▸ CXCR2 ▸
C9orf3 ▸ SH3D19 ▸ GIF ▸ THBD ▸ GHR ▸ CCL18 ▸ S11 ▸
GPX1 ▸ GAST ▸ ANXA5 ▸ CX3CL1 ▸ GATA3 ▸ GPX7 ▸ DDX58 ▸
COA1 ▸ PGP ▸ ACO1 ▸ GFAP ▸ HMGCR ▸ MRXS5 ▸ AGXT ▸
SMC3 ▸ TRAF1 ▸ COA4 ▸ BIRC3 ▸ CTRL ▸ CD19 ▸ JUND ▸
STX1A ▸ TYR ▸ CNP ▸ COA3 ▸ CCND2 ▸ MAP3K7 ▸ SMC2 ▸
FXR1 ▸ GPX2 ▸ ARC ▸ GATA2 ▸ ACHE ▸ LPO ▸ DDIT3 ▸
PRKAG1 ▸ PRKAB1 ▸ TSPO ▸ UPK3B ▸ PRKAA2 ▸ FPR1 ▸ ITGAX ▸
ISG15 ▸ PGC ▸ CES1 ▸ S12 ▸ MET ▸ CYBB ▸ EPB42 ▸
MARCKS ▸ GPX6 ▸ AQP5 ▸ UBL3 ▸ PRKAB2 ▸ CD28 ▸ ICOSLG ▸
CDH13 ▸ EIF4E ▸ MTA2 ▸ CTLA4 ▸ WNT2 ▸ CTSB ▸ SMC6 ▸
ALPI ▸ GPX8 ▸ PLAT ▸ CD1A ▸ GIT1 ▸ MT4 ▸ PLCG1 ▸
PTX4 ▸ IFIT2 ▸ HDAC6 ▸ GPX3 ▸ SMC5 ▸ NAALADL1 ▸ PRKAA1 ▸
CIITA ▸ VIPR1 ▸ ADCY9 ▸ TOLLIP ▸ FXR2 ▸ NEU3 ▸ RPTOR ▸
CAV2 ▸ CETP ▸ JAK3 ▸ NEU2 ▸ FGFR3 ▸ SMC4 ▸ POU2F2 ▸
SLC2A1 ▸ VIP ▸ GPX5 ▸ POMC ▸ CHD4 ▸ NPY4R ▸ SEC14L2 ▸
OXTR ▸ PLTP ▸ A2M ▸ PRDX1 ▸ ELAVL1 ▸ SCARB1 ▸ TECR ▸
JUNB ▸ CDC42 ▸ SIGIRR ▸ CYP2B6 ▸ CD8B ▸ TFRC ▸ S7 ▸
COA6 ▸ GSK3B ▸ GPX4 ▸ FADD ▸ SLC7A2 ▸ LOX ▸ PPARGC1A ▸
HP ▸ NPPA ▸ CD38 ▸ PRKAG2 ▸ CEBPZ ▸ NEU4 ▸ COA5 ▸
C4BPA ▸ EPB41 ▸ CCL4L2 ▸ PPP2R1A ▸ NDUFAB1 ▸ MAL ▸ PPARD ▸
HSP90AA1 ▸ PARP9 ▸ STAR ▸ CYP4F8 ▸ MCM7 ▸ ESAM ▸ FCGR1A ▸
ITGB1 ▸ ISG20 ▸ PARP11 ▸ IKBKE ▸ NCOR1 ▸ LAMP5 ▸ GALT ▸
AGT ▸ KITLG ▸ PRKCB ▸ PTHLH ▸ MUC5B ▸ CES2 ▸ ADCY1 ▸
IFN1@ ▸ CAPN9 ▸ MCM2 ▸ NPY ▸ AQP4 ▸ TFAP2A ▸ CAPN12 ▸
PRKAR2A ▸ ADCY10 ▸ AMBP ▸ CCL1 ▸ ETS1 ▸ PDGFB ▸ PTEN ▸
IL13RA1 ▸ VDR ▸ FEV ▸ RHOB ▸ IGH ▸ MCS ▸ PLEK ▸
SPAG8 ▸ SDC4 ▸ C1QB ▸ PRKACG ▸ CAPN10 ▸ CAPN1 ▸ CORO2A ▸
AKT1S1 ▸ PARP15 ▸ CAPN11 ▸ NTF3 ▸ ERP44 ▸ MST1R ▸ MTA1 ▸
PARP10 ▸ PVR ▸ ADAMTS5 ▸ MBD3 ▸ BDKRB1 ▸ MCM3 ▸ PRKAR2B ▸
MAP2K2 ▸ CAPN15 ▸ CPZ ▸ ADCY6 ▸ QRICH1 ▸ GATA1 ▸ CYP4F12 ▸
SIRT1 ▸ CLU ▸ PRKAR1A ▸ GATA6 ▸ PDGFA ▸ PARP4 ▸ KCNH4 ▸
CD5 ▸ EDNRA ▸ PARP2 ▸ PARP12 ▸ DST ▸ S1PR1 ▸ MCOLN1 ▸
CADM4 ▸ LAMP1 ▸ AQP2 ▸ G6PD ▸ MEPE ▸ C1QA ▸ MCM4 ▸
C5AR1 ▸ HDAC9 ▸ IL18BP ▸ AQP1 ▸ ADCY7 ▸ USP7 ▸ LGALS1 ▸
IDS ▸ CAPN6 ▸ CADM3 ▸ SLC9A1 ▸ SP100 ▸ ASS1 ▸ SST ▸
MLST8 ▸ OSM ▸ SMAD4 ▸ CTSL ▸ MTDH ▸ RASIP1 ▸ HDAC4 ▸
VWF ▸ LAMP3 ▸ HDAC10 ▸ QRICH2 ▸ PRDM1 ▸ GATA5 ▸ TUBGCP2 ▸
GPS2 ▸ CAPN5 ▸ ERF ▸ MAP2K6 ▸ TPGS2 ▸ IL2RG ▸ PMPCB ▸
CYP4F2 ▸ INSR ▸ SDC2 ▸ NTRK1 ▸ PPP2CA ▸ FGF2 ▸ PRX ▸
ABL1 ▸ CTNNB1 ▸ HDAC8 ▸ PKD2 ▸ SLC5A1 ▸ ACAN ▸ CAPN13 ▸
GLA ▸ CD1D ▸ PRKACB ▸ CD58 ▸ RPS6KB1 ▸ BCAP31 ▸ MAP2K3 ▸
CAPN7 ▸ LTC4S ▸ MCM6 ▸ CLDN1 ▸ SMN1 ▸ PECAM1 ▸ APOA1 ▸
PARP16 ▸ NPR1 ▸ HPGDS ▸ IRG1 ▸ KLF4 ▸ PDCD1LG2 ▸ SPHK2 ▸
PGR ▸ GATA4 ▸ EPS15 ▸ PLCG2 ▸ CX3CR1 ▸ ADCY3 ▸ PLA2G7 ▸
MARCO ▸ TRIM63 ▸ CYP4F22 ▸ ITGAL ▸ GSR ▸ NCF4 ▸ IL1RAP ▸
NQO1 ▸ PRTN3 ▸ ERP29 ▸ FGF21 ▸ CYP4F3 ▸ RSAD2 ▸ ELANE ▸
IL6R ▸ CYP4F11 ▸ MCM5 ▸ SREBF1 ▸ EPS8 ▸ PKD3 ▸ TXNRD2 ▸
FOXP3 ▸ MT-CYB ▸ TPO ▸ DOK3 ▸ ACSL1 ▸ TPGS1 ▸ HAMP ▸
SERPINB6 ▸ NR1I2 ▸ WNT5A ▸ RNPEP ▸ CES3 ▸ TNFSF13 ▸ RIPK2 ▸
TBL1X ▸ ADCY2 ▸ PARP14 ▸ PRDX5 ▸ SMAD7 ▸ PARP6 ▸ CAPN3 ▸
ADCY4 ▸ PARP8 ▸ CAPN14 ▸ PARP3 ▸ HDAC7 ▸ LAMP2 ▸ ADCY8 ▸
P2RX4 ▸ FMR1 ▸ REG3A ▸ PRKAR1B ▸ ADCY5 ▸ PIR ▸ PLN ▸
TPX2 ▸ S100A9 ▸ CNR1 ▸ FGF9 ▸ SLC11A2 ▸ CAPN2 ▸ KLK3 ▸
CPP ▸ AQP8 ▸ PDCD2 ▸ MICE ▸ NR4A1 ▸ TIMP3 ▸ KCNMA1 ▸
FST ▸ S1PR3 ▸ HDAC5 ▸ LGALS3 ▸ KHSRP ▸ ERP27 ▸ CAPN8 ▸
HCLS1 ▸ LRP1 ▸ RHO ▸ CADM2 ▸ CD9 ▸ PKD1 ▸ NANOS1 ▸
TBL1XR1 ▸ BCR ▸ F12 ▸ IL1R2 ▸ PPP2R2B ▸ FOSL1 ▸ CROT ▸
CYP1A2 ▸ CYP1A1 ▸ TAT ▸ USP14 ▸ NFKBIZ ▸ FPR2 ▸ GTF2A1 ▸
GPS1 ▸ COPS6 ▸ COPS5 ▸ COPS4 ▸ BNC2 ▸ ARHGAP29 ▸ RFX3 ▸
COPS2 ▸ PCAF ▸ SMARCD1 ▸ ZBTB3 ▸ GTF2E1 ▸ ONECUT1 ▸ CDK4 ▸
UBC ▸ MID1 ▸ TAF1 ▸ TLX2 ▸ NR3C1 ▸ CREBBP ▸ GTF3A ▸
Data information
Please see the Gene Interactions Track Manual.