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Wang et al., Am J Respir Cell Mol Biol 2006
(Inflammation) :
Gain-of-function experiments demonstrated that overexpression of caveolin-1 in RAW264.7 cells decreased LPS induced TNF-alpha and IL-6 production and augmented IL-10 production
Wu et al., J Neurosurg 2010
(Brain Injuries...) :
Simvastatin modified the caveolin-1 expression in lipid rafts in astrocyte cell membrane, suppressed the phosphorylation of EGFR in lipid rafts of astrocytes after OGD, and inhibited the OGD induced interleukin-1 production