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AHSA1 — APOB
Text-mined interactions from Literome
Hackeng et al., Thromb Haemost 1999
:
Integrins alphaIIbbeta3 and alpha2beta1, as well as the FcgammaRII-receptor, CD36 ( platelet glycoprotein IV ), CD68 ( gp110 ) and Low Density Lipoprotein-receptor related protein ( LRP ) were not implicated in
LDL induced
p38MAPK-activation
Zhu et al., Arterioscler Thromb Vasc Biol 2001
:
In this study, we demonstrated that
p38-ATF-2 is
activated by
LDL in human ECs and that this activation is mediated by Ras
Ryoo et al., Cardiovasc Res 2004
:
Although both
p38 and ERK 1/2 MAPKs were
activated by
LDL , only p38 MAPK is responsible for the LDL effects, as evidenced by a complete blockade of IL-8 upregulation by SB203580
Korporaal et al., J Biol Chem 2004
:
Furthermore, LDL bound efficiently to soluble apoER2 ', and the transient
LDL induced activation of
p38MAPK was mimicked by an anti-apoER2 antibody
BĂ©aslas et al., PloS one 2009
:
These early events included the trafficking of
apolipoprotein B , a structural component of TRL, from apical towards secretory domains, and the rapid, dose dependent
activation of ERK and
p38MAPK
Wang et al., Cardiovasc Drugs Ther 2013
(Atherosclerosis...) :
Furthermore, TMP suppressed
ox-LDL induced activations of p-ERK,
p-p38 , and p-JNK MAPK