Description

This track hub displays the GENCODE manual annotation of genes with potential links to SARS-CoV-2 infection or COVID-19 disease. It has been created in order to provide up to date annotation for these genes within 24 hours of changes being made, and these genes are currently being re-annotated in a systematic manner. We are both adding new transcript models and making changes to existing models, as appropriate.

The list of candidate genes can be found at the GENCODE website, along with further information on its creation. It has been extrapolated from recent publications and in collaboration with other projects, and we emphasise that it is not a set of genes with confirmed scientific or medical importance to infection or disease, rather a broadly curated list of genes that may be relevant. We expect that further genes will be added to the list as research into SARS-CoV-2 / COVID-19 continues, and we will update the GENCODE webpage as appropriate.

This work is being carried out according to our existing GENCODE annotation guidelines, and we are working to interpret the expression and function of each gene in a general scientific context. We do not offer any guidance as to which specific annotation changes may be of direct relevance to SARS-CoV-2 infection or COVID-19 disease.

The track hub data set contains annotation for only those genes that are included in our COVID-19 gene list. In the Track data view, transcript models that are unchanged with respect to release Ensembl 100 / GENCODEv34 are coloured blue, whereas new models or pre-existing models that have been modified are shown in orange.

Data access

The BED and GTF files for these annotations can be downloaded from this directory.

Contact

For more information, please contact GENCODE.