Male Donors Male 20-49 Yrs Track Settings
 
GTEx RNA-seq read coverage for male donor samples (20-49 years)

Track collection: GTEx RNA-seq from 371 Male Donors

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 All
Tissue
adiposeSubcut
adiposeVisceral
adrenalGland
arteryAorta
arteryCoronary
arteryTibial
bladder
brainAmygdala
brainAnCinCortex
brainCaudate
brainCerebelHemi
brainCerebellum
brainCortex
brainFrontCortex
brainHippocampus
brainHypothalamus
brainNucAccumbens
brainPutamen
brainSpinalcord
brainSubstanNigra
breastMamTissue
xformedlymphocytes
xformedfibroblasts
colonSigmoid
colonTransverse
esophagusJunction
esophagusMucosa
esophagusMuscular
heartAtrialAppend
heartLeftVentricl
kidneyCortex
liver
lung
minorSalivGland
muscleSkeletal
nerveTibial
pancreas
pituitary
prostate
skinNotExposed
skinExposed
smallIntestine
spleen
stomach
testis
thyroid
wholeBlood
Tissue
All 
Donor














































Donor
GTEX-11DXW 40 yrs   GTEX-11DXW 40 yrs
GTEX-11EQ9 30 yrs   GTEX-11EQ9 30 yrs
GTEX-11LCK 30 yrs   GTEX-11LCK 30 yrs
GTEX-11NSD 20 yrs   GTEX-11NSD 20 yrs
GTEX-11O72 40 yrs   GTEX-11O72 40 yrs
GTEX-11P7K 30 yrs   GTEX-11P7K 30 yrs
GTEX-11P82 20 yrs   GTEX-11P82 20 yrs
GTEX-11TT1 20 yrs   GTEX-11TT1 20 yrs
GTEX-11ZUS 30 yrs   GTEX-11ZUS 30 yrs
GTEX-12126 20 yrs   GTEX-12126 20 yrs
GTEX-12584 40 yrs   GTEX-12584 40 yrs
GTEX-12C56 20 yrs   GTEX-12C56 20 yrs
GTEX-12KS4 30 yrs   GTEX-12KS4 30 yrs
GTEX-12WSE 20 yrs   GTEX-12WSE 20 yrs
GTEX-12WSN 40 yrs   GTEX-12WSN 40 yrs
GTEX-1314G 30 yrs   GTEX-1314G 30 yrs
GTEX-1339X 40 yrs   GTEX-1339X 40 yrs
GTEX-1399Q 40 yrs   GTEX-1399Q 40 yrs
GTEX-1399R 30 yrs   GTEX-1399R 30 yrs
GTEX-13CZU 20 yrs   GTEX-13CZU 20 yrs
GTEX-13FTW 40 yrs   GTEX-13FTW 40 yrs
GTEX-13NYB 40 yrs   GTEX-13NYB 40 yrs
GTEX-13NZB 30 yrs   GTEX-13NZB 30 yrs
GTEX-13RTK 20 yrs   GTEX-13RTK 20 yrs
GTEX-13RTL 40 yrs   GTEX-13RTL 40 yrs
GTEX-13S86 40 yrs   GTEX-13S86 40 yrs
GTEX-144GM 20 yrs   GTEX-144GM 20 yrs
GTEX-145LT 40 yrs   GTEX-145LT 40 yrs
GTEX-145MN 30 yrs   GTEX-145MN 30 yrs
GTEX-146FQ 30 yrs   GTEX-146FQ 30 yrs
GTEX-14A6H 30 yrs   GTEX-14A6H 30 yrs
GTEX-14B4R 30 yrs   GTEX-14B4R 30 yrs
GTEX-14C39 40 yrs   GTEX-14C39 40 yrs
GTEX-14E6C 40 yrs   GTEX-14E6C 40 yrs
GTEX-14E6E 30 yrs   GTEX-14E6E 30 yrs
GTEX-14ICL 30 yrs   GTEX-14ICL 30 yrs
GTEX-NFK9 40 yrs   GTEX-NFK9 40 yrs
GTEX-NPJ8 40 yrs   GTEX-NPJ8 40 yrs
GTEX-O5YT 20 yrs   GTEX-O5YT 20 yrs
GTEX-OIZI 40 yrs   GTEX-OIZI 40 yrs
GTEX-OOBK 40 yrs   GTEX-OOBK 40 yrs
GTEX-P44G 30 yrs   GTEX-P44G 30 yrs
GTEX-P44H 40 yrs   GTEX-P44H 40 yrs
GTEX-PLZ6 30 yrs   GTEX-PLZ6 30 yrs
GTEX-PVOW 40 yrs   GTEX-PVOW 40 yrs
GTEX-PW2O 20 yrs   GTEX-PW2O 20 yrs
GTEX-Q2AH 40 yrs   GTEX-Q2AH 40 yrs
GTEX-Q2AI 40 yrs   GTEX-Q2AI 40 yrs
GTEX-QEG4 30 yrs   GTEX-QEG4 30 yrs
GTEX-QEG5 20 yrs   GTEX-QEG5 20 yrs
GTEX-QESD 20 yrs   GTEX-QESD 20 yrs
GTEX-QLQW 30 yrs   GTEX-QLQW 30 yrs
GTEX-QV31 30 yrs   GTEX-QV31 30 yrs
GTEX-R55C 40 yrs   GTEX-R55C 40 yrs
GTEX-R55E 20 yrs   GTEX-R55E 20 yrs
GTEX-RWSA 40 yrs   GTEX-RWSA 40 yrs
GTEX-S33H 30 yrs   GTEX-S33H 30 yrs
GTEX-S4Q7 20 yrs   GTEX-S4Q7 20 yrs
GTEX-SNMC 20 yrs   GTEX-SNMC 20 yrs
GTEX-SNOS 40 yrs   GTEX-SNOS 40 yrs
GTEX-T5JC 20 yrs   GTEX-T5JC 20 yrs
GTEX-T8EM 40 yrs   GTEX-T8EM 40 yrs
GTEX-TKQ1 30 yrs   GTEX-TKQ1 30 yrs
GTEX-U3ZH 30 yrs   GTEX-U3ZH 30 yrs
GTEX-U3ZM 40 yrs   GTEX-U3ZM 40 yrs
GTEX-U4B1 40 yrs   GTEX-U4B1 40 yrs
GTEX-U8XE 30 yrs   GTEX-U8XE 30 yrs
GTEX-UPK5 40 yrs   GTEX-UPK5 40 yrs
GTEX-VUSH 30 yrs   GTEX-VUSH 30 yrs
GTEX-WFG7 20 yrs   GTEX-WFG7 20 yrs
GTEX-WFG8 20 yrs   GTEX-WFG8 20 yrs
GTEX-WFJO 30 yrs   GTEX-WFJO 30 yrs
GTEX-WFON 40 yrs   GTEX-WFON 40 yrs
GTEX-WH7G 40 yrs   GTEX-WH7G 40 yrs
GTEX-WHSE 20 yrs   GTEX-WHSE 20 yrs
GTEX-WOFM 20 yrs   GTEX-WOFM 20 yrs
GTEX-WZTO 40 yrs   GTEX-WZTO 40 yrs
GTEX-X3Y1 40 yrs   GTEX-X3Y1 40 yrs
GTEX-X5EB 40 yrs   GTEX-X5EB 40 yrs
GTEX-X88G 30 yrs   GTEX-X88G 30 yrs
GTEX-XAJ8 40 yrs   GTEX-XAJ8 40 yrs
GTEX-XBEW 40 yrs   GTEX-XBEW 40 yrs
GTEX-XK95 40 yrs   GTEX-XK95 40 yrs
GTEX-XMK1 40 yrs   GTEX-XMK1 40 yrs
GTEX-XPT6 20 yrs   GTEX-XPT6 20 yrs
GTEX-XQ3S 20 yrs   GTEX-XQ3S 20 yrs
GTEX-Y8E4 40 yrs   GTEX-Y8E4 40 yrs
GTEX-Y9LG 30 yrs   GTEX-Y9LG 30 yrs
GTEX-YB5E 40 yrs   GTEX-YB5E 40 yrs
GTEX-YEC4 40 yrs   GTEX-YEC4 40 yrs
GTEX-YFCO 40 yrs   GTEX-YFCO 40 yrs
GTEX-YJ8A 20 yrs   GTEX-YJ8A 20 yrs
GTEX-Z9EW 40 yrs   GTEX-Z9EW 40 yrs
GTEX-ZA64 20 yrs   GTEX-ZA64 20 yrs
GTEX-ZAB4 40 yrs   GTEX-ZAB4 40 yrs
GTEX-ZLFU 40 yrs   GTEX-ZLFU 40 yrs
GTEX-ZPU1 40 yrs   GTEX-ZPU1 40 yrs
GTEX-ZQUD 30 yrs   GTEX-ZQUD 30 yrs
GTEX-ZT9X 40 yrs   GTEX-ZT9X 40 yrs
GTEX-ZTSS 40 yrs   GTEX-ZTSS 40 yrs
GTEX-ZTX8 20 yrs   GTEX-ZTX8 20 yrs
GTEX-ZU9S 30 yrs   GTEX-ZU9S 30 yrs
GTEX-ZUA1 40 yrs   GTEX-ZUA1 40 yrs
GTEX-ZVTK 20 yrs   GTEX-ZVTK 20 yrs
GTEX-ZVZO 40 yrs   GTEX-ZVZO 40 yrs
GTEX-ZWKS 30 yrs   GTEX-ZWKS 30 yrs
GTEX-ZYT6 30 yrs   GTEX-ZYT6 30 yrs
GTEX-ZZ64 20 yrs   GTEX-ZZ64 20 yrs
Donor














































Donor
 All
Tissue
adiposeSubcut
adiposeVisceral
adrenalGland
arteryAorta
arteryCoronary
arteryTibial
bladder
brainAmygdala
brainAnCinCortex
brainCaudate
brainCerebelHemi
brainCerebellum
brainCortex
brainFrontCortex
brainHippocampus
brainHypothalamus
brainNucAccumbens
brainPutamen
brainSpinalcord
brainSubstanNigra
breastMamTissue
xformedlymphocytes
xformedfibroblasts
colonSigmoid
colonTransverse
esophagusJunction
esophagusMucosa
esophagusMuscular
heartAtrialAppend
heartLeftVentricl
kidneyCortex
liver
lung
minorSalivGland
muscleSkeletal
nerveTibial
pancreas
pituitary
prostate
skinNotExposed
skinExposed
smallIntestine
spleen
stomach
testis
thyroid
wholeBlood
Tissue
All 
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  Tissue↓1 ↓2 Age↓3 Donor↓4   Track Name↓5  
 
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 adiposeVisceral      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Adipose - Visceral (Omentum) (GTEX-ZAB4-1426-SM-5CVN6)   Data format 
 
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 arteryCoronary      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Artery - Coronary (GTEX-ZAB4-0726-SM-5HL8I)    Data format 
 
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 arteryTibial      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Artery - Tibial (GTEX-ZAB4-1926-SM-57WD8)    Data format 
 
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 brainAnCinCortex      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Anterior cingulate cortex (BA24) (GTEX-ZAB4-0011-R3a-SM-4RGNQ)    Data format 
 
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 brainCaudate      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Caudate (basal ganglia) (GTEX-ZAB4-0011-R5a-SM-4SOKC)    Data format 
 
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 brainCerebelHemi      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Cerebellar Hemisphere (GTEX-ZAB4-0011-R11a-SM-4SOKI)    Data format 
 
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 brainCerebellum      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Cerebellum (GTEX-ZAB4-2926-SM-57WCV)    Data format 
 
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 brainFrontCortex      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Frontal Cortex (BA9) (GTEX-ZAB4-0011-R10a-SM-4SOKH)    Data format 
 
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 brainHypothalamus      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Hypothalamus (GTEX-ZAB4-0011-R8b-SM-4SOKF)    Data format 
 
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 brainNucAccumbens      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Nucleus accumbens (basal ganglia) (GTEX-ZAB4-0011-R6a-SM-4SOKD)    Data format 
 
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 brainPutamen      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Putamen (basal ganglia) (GTEX-ZAB4-0011-R7a-SM-4SOKE)    Data format 
 
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 brainSpinalcord      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Spinal cord (cervical c-1) (GTEX-ZAB4-0011-R9a-SM-4SOKG)    Data format 
 
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 brainSubstanNigra      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Brain - Substantia nigra (GTEX-ZAB4-0011-R2a-SM-4RGNP)    Data format 
 
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 colonSigmoid      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Colon - Sigmoid (GTEX-ZAB4-2426-SM-5HL8A)    Data format 
 
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 colonTransverse      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Colon - Transverse (GTEX-ZAB4-2226-SM-5HL97)    Data format 
 
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 esophagusMucosa      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Esophagus - Mucosa (GTEX-ZAB4-1126-SM-5HL86)    Data format 
 
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 heartAtrialAppend      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Heart - Atrial Appendage (GTEX-ZAB4-0926-SM-5CVN4)    Data format 
 
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 heartLeftVentricl      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Heart - Left Ventricle (GTEX-ZAB4-1026-SM-5HL7T)    Data format 
 
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 liver      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Liver (GTEX-ZAB4-0826-SM-5LU9D)    Data format 
 
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 lung      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Lung (GTEX-ZAB4-0626-SM-5CVN3)    Data format 
 
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 muscleSkeletal      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Muscle - Skeletal (GTEX-ZAB4-0426-SM-5HL7N)    Data format 
 
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 nerveTibial      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Nerve - Tibial (GTEX-ZAB4-1826-SM-5HL8O)    Data format 
 
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 pancreas      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Pancreas (GTEX-ZAB4-1726-SM-5HL8C)    Data format 
 
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 pituitary      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Pituitary (GTEX-ZAB4-3126-SM-57WCJ)    Data format 
 
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 skinExposed      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Skin - Sun Exposed (Lower leg) (GTEX-ZAB4-0226-SM-5N9F5)    Data format 
 
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 skinNotExposed      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Skin - Not Sun Exposed (Suprapubic) (GTEX-ZAB4-2126-SM-5HL8U)    Data format 
 
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 testis      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Testis (GTEX-ZAB4-0126-SM-5CVMG)    Data format 
 
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 xformedfibroblasts      40-49  GTEX-ZAB4 40 yrs  GTEx RNA signal from male Cells - Transformed fibroblasts (GTEX-ZAB4-0008-SM-4RGM6)    Data format 
    
Assembly: Human Dec. 2013 (GRCh38/hg38)

Description

The NIH Genotype-Tissue Expression (GTEX) project was created to establish a sample and data resource for studies on the relationship between genetic variation and gene expression in multiple human tissues. This track hub shows RNA-seq read coverage signal graphs of GTEx samples in the GTEx midpoint milestone data release (V6, October 2015). A total of 7572 tracks representing samples from 570 adult post-mortem individuals are included.

Display Conventions

The individual sample tracks are organized by gender (Female Donors, Male Donors) and age, in 6 tracks, where samples can be selected from a donor vs. tissue matrix.

  • Female 20-49 yrs
  • Female 50-59 yrs
  • Female 60-69 yrs
  • Male 20-49 yrs
  • Male 50-59 yrs
  • Male 60-69 yrs
An alternative organization is provided by the 'By Tissues' supertrack set, which consists of a track containing all samples for each of the 53 tissues, with a selection matrix of donor gender and age.

Methods

Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen. All tissue specimens were reviewed by pathologists to characterize and verify organ source. Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules.

The Illumina TruSeq protocol was used to create an unstranded polyA+ library sequenced on the Illumina HiSeq 2000 platform to produce 76-bp paired end reads at a depth averaging 50M aligned reads per sample.

Sequence reads for this track were aligned to the hg38/GRCh38 human genome using STAR2 assisted by the GENCODE v24 transcriptome definition. The read coverage signal graphs were produced using the --outWig option of STAR2. Read mapping was performed at UCSC by the Computational Genomics lab, using the Toil pipeline. The resulting bedGraph files were converted to bigWig format for display. The bedGraph files were coordinate converted to the hg19/GRCh37 assembly via the UCSC liftOver tool.

Subject and Sample Characteristics

The scientific goal of the GTEx project required that the donors and their biospecimen present with no evidence of disease. The tissue types collected were chosen based on their clinical significance, logistical feasibility and their relevance to the scientific goal of the project and the research community. Postmortem samples were collected from non-diseased donors with ages ranging from 20 to 79. 34.4% of donors were female and 65.6% male.

Additional summary plots of GTEx sample characteristics are available at the GTEx Portal Tissue Summary page.

Credits

Samples were collected by the GTEx Consortium. RNA-seq was performed by the GTEx Laboratory, Data Analysis and Coordinating Center (LDACC) at the Broad Institute. John Vivian, Melissa Cline, and Benedict Paten of the UCSC Computational Genomics lab were responsible for the sequence read mapping and signal file generation used to produce this hub. Kate Rosenbloom and Parisa Nejad of the UCSC Genome Browser group were responsible for data file post-processing and track hub configuration.

Contacts

For questions about the GTEx data, contact the GTEx LDACC at the Broad Institute. For questions about this track hub, contact the UCSC Genome Browser mailing list.

References

GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat Genet. 2013 Jun;45(6):580-5. PMID: 23715323; PMC: PMC4010069

Carithers LJ, Ardlie K, Barcus M, Branton PA, Britton A, Buia SA, Compton CC, DeLuca DS, Peter-Demchok J, Gelfand ET et al. A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project. Biopreserv Biobank. 2015 Oct;13(5):311-9. PMID: 26484571; PMC: PMC4675181

Melé M, Ferreira PG, Reverter F, DeLuca DS, Monlong J, Sammeth M, Young TR, Goldmann JM, Pervouchine DD, Sullivan TJ et al. Human genomics. The human transcriptome across tissues and individuals. Science. 2015 May 8;348(6235):660-5. PMID: 25954002; PMC: PMC4547472

DeLuca DS, Levin JZ, Sivachenko A, Fennell T, Nazaire MD, Williams C, Reich M, Winckler W, Getz G. RNA-SeQC: RNA-seq metrics for quality control and process optimization. Bioinformatics. 2012 Jun 1;28(11):1530-2. PMID: 22539670; PMC: PMC3356847