Description

High-depth sequence reads from the Celera project were used to detect paralogy in the human genome reference sequence. This track shows confirmed segmental duplications, defined as having similarity to sequences in the Segmental Duplication Database (SDD) of greater than 90% over more than 250 bp of repeatmasked sequence. For a description of the whole-genome shotgun sequence detection (WSSD) "fuguization" method, see Bailey, J.A. et al. (2001) in the References section below.

Credits

The data were provided by Xinwei She and Evan Eichler as part of their efforts to map human paralogy at the University of Washington.

References

Bailey, J.A., et al., Recent segmental duplications in the human genome. Science 297(5583), 945-7 (2002).

Bailey, J.A., et al., Segmental duplications: organization and impact within the current human genome project assembly, Genome Res. 11(6), 1005-17 (2001).

She, X., et al., Shotgun sequence assembly and recent segmental duplications within the human genome. Nature 431(7011), 927-30 (2004).