Description
Most proteins are composed of one or more conserved functional regions called
domains. This track shows the high-quality, manually curated
Pfam-A
domains found in transcripts from the NCBI Genes track.
Display Conventions and Configuration
This track follows the display conventions for
gene tracks.
Methods
The amino acid sequences from the NCBI Genes
are submitted to the set of Pfam-A HMMs, which annotate regions within the
predicted peptide that are recognizable as Pfam protein domains. These regions
are then mapped to the transcripts themselves using the
pslMap utility.
Credits
pslMap was written by Mark Diekhans at UCSC.
References
Finn RD, Mistry J, Tate J, Coggill P, Heger A, Pollington JE, Gavin OL, Gunasekaran P, Ceric G,
Forslund K et al.
The Pfam protein families database.
Nucleic Acids Res. 2010 Jan;38(Database issue):D211-22.
PMID: 19920124; PMC: PMC2808889
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