◀ Back to IFNG

IFNG — IRF5

Text-mined interactions from Literome

Kano et al., Biochem Biophys Res Commun 1999 : Taken together, IRF-1 mediates IFN-gamma signaling into primary hepatocytes for cell cycle arrest via p53 expression and for apoptosis
Green et al., Leukemia 1999 (Chromosome Deletion...) : Unexpectedly, all primary acute promyelocytic leukemia ( APL ) samples lacked IRF-1 protein and most exhibited accelerated exon skipping ; furthermore, IRF-1 could not be induced by IFNgamma or all-trans retinoic acid ( ATRA ) which both induce IRF-1 in the NB4 APL cell line
Jarosinski et al., J Neuroimmunol 2002 : MHC class I gene promoter activity in astrocytes was controlled entirely through a single enhancer, the MHC-IRF-E , to which IRF-1 bound in response to IFN-gamma in wild type but not in IRF-1 ( -/- ) mouse astrocytes
Sheikh et al., Cardiovasc Res 2005 (Arteriosclerosis) : Northern blotting showed that lysoPC transiently and dose-dependently inhibited the IFN gamma induced accumulation of IP-10, Mig and I-Tac but not p48, interferon regulatory factor-1 and guanidine binding protein-1
Shi et al., Int J Biochem Cell Biol 2006 (Breast Neoplasms...) : Both treatments induced USF-1 and IRF binding complexes to promoter IV but only IFNgamma induced the binding of 435-Lung2 nuclear proteins to an ARE-1 site at the promoter III
Bennett et al., Blood 2006 (Inflammation...) : Thus, knock-down of RAX expression by 80 % using small interfering RNA ( siRNA ) prevents IFNgamma/tumor necrosis factor alpha (TNFalpha) induced PKR activation and eIF2alpha phosphorylation, IkappaB degradation, IRF-1 expression, and STAT1 phosphorylation, resulting in enhanced murine embryonic fibroblast (MEF) cell survival
Buckley et al., Mol Cancer Res 2007 : Using an Affymetrix U95A microarray, IRF-7 was identified as a BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence of IFN-gamma , coincident with the synergistic induction of apoptosis
Schedel et al., Am J Respir Crit Care Med 2008 (Genetic Predisposition to Disease...) : Our results suggest that functionally relevant IRF-1 polymorphisms influence atopy risk, potentially by altering transcription factor binding, IRF-1 gene expression, and IFN-gamma regulation
Shultz et al., J Interferon Cytokine Res 2009 : Roles of IKK-beta, IRF1 , and p65 in the activation of chemokine genes by interferon-gamma
Faure et al., J Biol Chem 1999 : The decrease of LPS/IFN-gamma induced IRF-1 promoter activity, IRF-1 synthesis, and IRF-1 activation, by PDTC, genistein, PD98059, and SB 203580, could explained in part the inhibition of the NOS-2 induction by these compounds